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Xylazine-CAS 7361-61-7

Short Description:

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats. Xylazine is often used for veterinary anesthesia.


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Usage:

Xylazine is α2 class of adrenergic receptor agonist.Target: Adrenergic ReceptorXylazine is a drug that is used for sedation,anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of
clonidine, it is an agonist at the α2 class of adrenergic receptor.Higher doses of xylazine caused mild hind limb ataxia. Administration of lidocaine induced a similar duration of analgesia, with
severe hind limb ataxia (100% incidence). We concluded that xylazine given by epidural injection results in safe, effective perineal analgesia in horses.

TEST SPECIFICATIONS RESULTS
Characters A white or almost white
Crystalline powder,
Hygroscopic. Freely soluble
in water, very soluble in methanol, freely soluble in methylene chloride.
Conform
Identification A) IR graph should be concordant
with reference spectrum of Xylazine Hydrochloride.
B) the paper turns violet-red.
Conform
Appearance of solution Solution S should not be more
opalescent than reference
Suspension II and should be colourless.
Conform
pH 4.5 to 5.5 5.1
Impurity A Not more than 100 ppm. Conform
Related substances A) Impurities C and E (for each impurity): Not more than 0.2%.
B) Impurities B and D (for each impurity): Not more than 0.2%.
C) Any other impurity: Not more than 0.2%.
D) Total impurities other
Than B,C,D and E : Not more than 0.2%.
Conform
Loss on drying Not more than 0.5% 0.32%
Heavy metals Not more than 10ppm Complies
Sulphated ash Not more than 0.100% 0.02%
Assay 98.0% ~ 102.0%
Calculated on dried basis
99.97%
Residual solvents
Acetone
Xylene
Not more than 300ppm
Not more than 300ppm
Not more than 300ppm
Not more than 300ppm
Conforms
Conforms
Conforms
Conforms
BIOLOGICAL TESTS NOT MORE THAN 104 EU/g Conform

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