Xylazine-CAS 7361-61-7
Usage:
Xylazine is α2 class of adrenergic receptor agonist.Target: Adrenergic ReceptorXylazine is a drug that is used for sedation,anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of
clonidine, it is an agonist at the α2 class of adrenergic receptor.Higher doses of xylazine caused mild hind limb ataxia. Administration of lidocaine induced a similar duration of analgesia, with
severe hind limb ataxia (100% incidence). We concluded that xylazine given by epidural injection results in safe, effective perineal analgesia in horses.
TEST | SPECIFICATIONS | RESULTS |
Characters | A white or almost white Crystalline powder, Hygroscopic. Freely soluble in water, very soluble in methanol, freely soluble in methylene chloride. |
Conform |
Identification | A) IR graph should be concordant with reference spectrum of Xylazine Hydrochloride. B) the paper turns violet-red. |
Conform |
Appearance of solution | Solution S should not be more opalescent than reference Suspension II and should be colourless. |
Conform |
pH | 4.5 to 5.5 | 5.1 |
Impurity A | Not more than 100 ppm. | Conform |
Related substances | A) Impurities C and E (for each impurity): Not more than 0.2%. B) Impurities B and D (for each impurity): Not more than 0.2%. C) Any other impurity: Not more than 0.2%. D) Total impurities other Than B,C,D and E : Not more than 0.2%. |
Conform |
Loss on drying | Not more than 0.5% | 0.32% |
Heavy metals | Not more than 10ppm | Complies |
Sulphated ash | Not more than 0.100% | 0.02% |
Assay | 98.0% ~ 102.0% Calculated on dried basis |
99.97% |
Residual solvents Acetone Xylene |
Not more than 300ppm Not more than 300ppm Not more than 300ppm Not more than 300ppm |
Conforms Conforms Conforms Conforms |
BIOLOGICAL TESTS | NOT MORE THAN 104 EU/g | Conform |
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